MeSsy with Christina Applegate & Jamie Lynn Sigler

How to Feel Safe in Your Body with Deb Dana (Re-Release)
Nov 25, 2025 · 5047

This week, Christina and Jamie are revisiting their conversation with Deb Dana, LCSW, a clinician and speaker specializing in complex trauma. They discuss how to understand our nervous systems, polyvagal theory, how to …

You Don’t Deserve to Feel Guilt
Nov 18, 2025 · 4020

This week, Christina and Jamie read listener emails and discuss big feelings, reality dating shows, guilt, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: …

Best of MeSsy: Edie Falco, Jean Smart, and Katey Sagal
Nov 11, 2025 · 4317

This week, we revisit conversations with three incredible guests: Edie Falco, Jean Smart, and Katey Sagal. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Wind…

Robert Iler
Nov 4, 2025 · 3663

This week, Christina and Jamie are joined by Robert Iler, who starred on "The Sopranos" with Jamie. They discuss memories from their time on the show, his path to becoming sober, his friendship with Jamie, and much more…

How Vulnerable Can I Be? with Craig Thomas
Oct 28, 2025 · 4494

This week Christina and Jamie are joined by Craig Thomas, an author and Co-Creator, Executive Producer and Writer of How I Met Your Mother. He shares his experience raising a son with Jacobsen Syndrome, discusses the p…

We Don’t Move Past It, We Move With It
Oct 21, 2025 · 3452

This week, Christina and Jamie read listener emails and discuss aging, being able to express emotions authentically, where to turn when you’re feeling stuck, and more. Executive Producers: Christina Applegate, Jamie …

Everybody’s Got Something
Oct 14, 2025 · 3923

This week, Christina and Jamie read listener emails and discuss dynamic disability, not being alone in your struggles, the meaning we attach to things, and more. Executive Producers: Christina Applegate, Jamie Lynn S…

It’s Okay to Be Yourself with Baylen Dupree
Oct 7, 2025 · 3064

This week Christina and Jamie are joined by Baylen Dupree. She opens up about having Tourette syndrome, the importance of being yourself, why it's crucial to remember that everyone is struggling, and more. Executive …

Megan Mullally
Sep 30, 2025 · 3703

This week Christina and Jamie are joined by Megan Mullally. They discuss how her role as Karen on Will & Grace came to be, understanding family trauma, the comfort of TV, and more. Executive Producers: Christina Appl…

Do What You Can When You Can
Sep 23, 2025 · 3101

This week Christina and Jamie are joined by Christina’s friend, Cindy Locke. They share how they first connected online and discuss the impact of trauma, advice to people who are newly diagnosed, the importance of suppo…

Fraser Olender
Sep 16, 2025 · 3354

This week, Christina and Jamie are joined by Fraser Olender from “Below Deck.” They discuss what his job as chief stew actually entails, his journey to find his true self, the escape of being busy, and much more. Exe…

We Are Not the Things That Happen to Us
Sep 9, 2025 · 3370

This week, Christina and Jamie read listener emails and discuss conditional friends, not identifying as the things that happen to us, staying honest, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigle…

Change Your Brain, Change Your Pain with Dr. Daniel Amen
Sep 2, 2025 · 4182

This week, Christina and Jamie are joined by Dr. Daniel Amen, a physician, double board-certified psychiatrist, and award-winning researcher. They discuss why pain can also live in your brain, the doom loop and how to g…

We Have to Pivot
Aug 26, 2025 · 3745

This week, Christina and Jamie read listener emails and discuss their kids starting the new school year, the power of manifestation, accepting reality, and much more. Executive Producers: Christina Applegate, Jamie L…

I Just Wanna Be Stoned
Aug 19, 2025 · 3563

This week, Christina and Jamie read listener emails and discuss hormones, housewives, acknowledging the struggle, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engin…

Ed Helms
Aug 12, 2025 · 5269

This week, Christina and Jamie are joined by Ed Helms. They discuss working together on "Vacation," his love of comedy, the importance of curiosity, and much more. Executive Producers: Christina Applegate, Jamie Lynn…

Live From the Hospital
Aug 5, 2025 · 4180

This week, Christina joins Jamie live from the hospital in LA. They discuss what Christina’s going through, her recent trip abroad, their upcoming memoirs, the way the universe works, and much more. Executive Produce…

Jenny Mollen
Jul 29, 2025 · 4260

This week, Christina and Jamie are joined by Jenny Mollen, a New York Times bestselling author and actor. They discuss the feeling of not being in control, the trials of parenting, and more. Executive Producers: Christ…

Easy on My Nervous System
Jul 22, 2025 · 3852

This week, Christina and Jamie read listener emails and discuss wins and losses, shows that are easy on the nervous system, why people don't understand invisible diseases, and much more. Executive Producers: Christina …

Any Movement Counts with Doctor Gretchen
Jul 15, 2025 · 4321

This week, Christina and Jamie are joined by Dr. Gretchen Hawley, an MS-certified specialist and physical therapist. They discuss what to do if you're feeling overwhelmed, the importance of staying consistent, why minds…

MeSsy with Christina Applegate & Jamie Lynn Sigler

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